COMMONLY USED CRITICAL CARE INFUSIONS

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Drug	Dose	Fluid	To yield	Calculation Constant	Usual DoseRange	Other information
Dopamine (Inotropin)	400 mg	D5W 250cc	1.6 mg/cc	26.7 mcg/mcgtt:weight	2 - 20 mcg/kg/min	<3 mcg renal dose >7 mcg begins to impair renal circulation.
Sodium Nitroprusside (Nipride)	50 mg	D5W 250cc	0.2mg/cc	3.3 mcg/mcgtt:weight	0.5 - 8 mcg/kg/min	1)Protect from light 2)Monitor serum Thiocyanate levels.
Dobutamine (dobutrex)	250 mg	D5W 250cc	1 mg/cc	16.7 mcg/mcgtt:weight	2.5 -10 mcg/kg/min	Inotropic Agent
Epinephrine (Adrenelin)	2 mg	D5W 250 cc	8 mcg/cc	0.13 mcg/mcgtt:weight	1 - 4 mcg/min	Large doses produce vasoconstriction Small doses produce vasodilation
Isopreterenol (Isuprel)	2 mg	D5W 250 cc	8 mcg/cc	0.13 mcg/mcgtt:weight	2 -10 mcg/min	use with caution in patients who are experiencing VPCs. Increases possibility of VT/VF.
Norepinephrine (Levophed)	2 mg	D5W 250cc	8 mcg/cc	0.13 mcg/mcgtt:weight	2 -12 mcg/min	May be titrated to higher doses
Phenylephrine (Neosnyphrine)	20 mg	D5W 250cc	80 mcg/cc	1.3 mcg/mcgtt:weight	10 -20 mcg/min	Higher doses may be ordered
Amrinone	500 mg	NS100cc to make 200cc volume	2.5 mg/cc	41.7 mcg/mcgtt:weight	2 - 20 mcg/min	Loading dose 0.75 mg/kg. must be mixed in NS or .45 NS
Nitroglycerin (Tridil)	50 mg	D5W 250 cc	200 mcg/cc	3.33 mcg/mcgtt:weight	5 - 200 mcg/min	Must be mixed in glass bottle & administered is special tubing
Lidocaine (xylocaine)	2 Grams	D5W 250cc	8 mg/cc	0.13 mg/mcgtt:weight	1 - 4 mg/min	Loading dose: 1 mg/kg up to 3 mg/kg
Procanamide (Pronestyl)	2 Grams	D5W 250cc	8 mg/cc	0.13 mg/mcgtt:weight	1 - 4 mg/min	Loading Dose: 20 mg/min up to 1 gram
Bretylium (Bretylol)	2 Grams	D5W 250cc	8 mg/cc	0.13 mg/mcgtt:weight	1 - 2 mg/min	Loading Dose: 5 mg/kg up to 30 mg/kg
Vasopressin (Pitressin)	200 IU	D5W 250cc	0.8 units/cc	0.013 units/mcgtt:weight	0.2 - 0.4 units/min	Must be aqueous pitressin
Labetalol (Trandate)	300 mg	D5W 240cc to make 300c total volume	1 mg/cc	16.7/mcgtt:weight	2 mg/min	Loading Dose: 20 mg up to 80 mg
Esmolol (Brevibloc)	5 Grams	D5W 500 cc	10 mg/cc	167 mcg/mcgtt:weight	50 - 200 mcg/kg/min	short acting Beta Blocker
Diltiazem (Cardizem)	125 mg	D5W 100 cc qs to make 125cc volume	1 mg/cc	16.7 mcg/mcgtt:weight	10 - 15 mg/ hr	can also be used for atrial arrythmias & SVT
Heparin	25,000 units	D5W 250 cc	100 units/cc	----	Given based on protocol. adjusted per nomogram based on PTT	watch carefully for signs of bleeding
Insulin	100 units	NS 100cc	1 unit/cc	----	Given based on orders, sliding scale adjusted per Capillary Blood Glucose readings	watch for hypoglycemia
Amiodarone (Cordarone)	450 mg	250 cc	----	----	1 mg/min for 6 hours @33 cc/hr then reduce to 0.5 mg/min @17 cc/hr	watch for hypotension
Propofol (Diprivan)	1000 mg	100cc	10 mg/cc	167mcg/mcgtt:weight	titrate to sedation	control according to Ramsey sedation scale